Syrian Rue, scientifically known as Peganum harmala, is a plant indigenous to the Middle East and South Asia. These seeds are small and brownish and contain psychoactive compounds, primarily harmine and harmaline, which act as Monoamine Oxidase inhibitors (MAOIs). Syrian Rue has a rich history of traditional use, both in medicine and spirituality. It has been employed in diverse cultures for its potential therapeutic benefits, such as treating digestive and respiratory conditions. In certain religious and shamanic ceremonies, Syrian Rue seeds are utilized, often in combination with other plants like Psychotria viridis, to create the hallucinogenic brew known as Ayahuasca.
When consumed, Syrian Rue seeds can induce altered states of consciousness, vivid dreams, and visual hallucinations due to their MAOI activity. Their primary psychoactive action is the inhibition of monoamine oxidase enzymes, which leads to an increased bioavailability of certain neurotransmitters like serotonin and dopamine. However, it’s crucial to approach their use with caution, as they can interact dangerously with certain foods and medications.
WARNING: Despite its purported medicinal uses, the seeds are extremely dangerous to ingest. They contain MAOI’s that can prevent the breakdown of toxic substances, rendering certain foods and medicines toxic. Keep away from children and curious pets. Not for Human Consumption. Information, statements and products on this website have not been evaluated by the FDA and are not intended to diagnose, mitigate, treat, cure, or prevent any disease or health condition.